�Tibolone, a synthetic do drugs used in many countries mainly to treat menopausal symptoms, reduces the risk of fractures and breast cancer, merely also increases the endangerment of cerebrovascular accident in elderly women. Those are the findings of a study published in the August 14th topic of the New England Journal of Medicine
Researchers recruited 4,538 women, between the ages of 60 and 85 years, in 22 countries for this randomized, double blind study. Half were minded 1.25 mg of tibolone casual, half were given an identical placebo. Those given tibolone had a decreased risk of vertebral fractures by 45% and the risk of other types of fractures by 26%.
In addition tibolone reduced the risk of breast crab. The force of tibolone was corresponding to those seen in women given the drugs tamoxifen or raloxifene.
"The reduction in breast cancer risk of exposure was a surprise to us," says Steven R. Cummings, M.D., of the California Pacific Medical Center Research Institute and the lead writer of the study. "We don't know how tibolone reduces chest cancer risk. Understanding its mechanism power point us toward new ways to prevent the disease." In addition, the rate of colon genus Cancer was lower in women who received tibolone. The mechanism for this effect is too unknown.
However, the drug came with a significant face effect: the rate of stroke was 2.3 per 1,000 woman-years higher in women taking tibolone than those taking placebo, representing a doubling of the risk of stroke. The study did not include women under age 60, so cannot determine whether tibolone significantly increases that risk in that eld group.
Even so, Dr. Cummings says tibolone may still have some value for younger women. "Stroke is very rare among women under age 60, so although taking tibolone does slightly increase the risk for women in their 50's, the benefits of treatment for bothersome menopausal symptoms would outweigh those risks."
Dr. Cummings says the drug should not be given to women wHO have risk factors for stroke, such as high blood pressure or diabetes, nor should it be continued after age 65.
Tibolone is currently approved in 90 countries worldwide for the treatment of menopausal symptoms, and in 45 countries to prevent osteoporosis. It is not usable in the United States.
California Pacific Medical Center. Beyond Medicine
At San Francisco's California Pacific Medical Center, we believe in the power of medicine. We research the most up-to-date treatments, lease the most qualified individuals, and practice the most modern, innovative medicine available. We deliver the highest quality technical care, with kindness and compassion, in acute, post-acute and outpatient services, as well as preventive and complementary music. But we also believe that medicinal drug alone is only part of the solution. That's why we look intently at each individual case and treat the whole person, not just the illness. It's why we go beyond medical maintenance and provide our patients with things like disease counseling, household support and wellness treatments. As one and only of California's largest secret, community-based, not-for-profit, teaching aesculapian centers, and a Sutter Health affiliate, we are able to reach recondite into our community to provide department of Education, screening and financial support in some of the city's most underserved neighborhoods. Because medicine can transmute a dead body. But leaving beyond medicine can translate a life.
California Pacific Medical Center
PO Box 7999
San Francisco, CA 94120-7999
United States
http://www.cpmc.org
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Thursday 14 August 2008
Wednesday 6 August 2008
Jussi Polet
Artist: Jussi Polet
Genre(s):
Trance
Discography:
Big City EP
Year: 2006
Tracks: 4
Kanye West, Nine Inch Nails � But Not Barack Obama � Close Out Lollapalooza 2008
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